Appropriate for general management courses emphasizing lean operations strategy implementation and large-scale change management across a network of global manufacturing facilities. In the (A) case, OM 1402, students critique the progress of Operational Transformation Excellence at three first-wave sites in New York and Puerto Rico and offer suggestions for a continuation of the rollout across other Wyeth sites. In this (B) case, the head of TO&PS reviews the best practices and insights gained during the first and second waves before heading into the third and fourth waves of the transformation. A teaching note (OM-1400TN) is available.